NEW PAPER: Yuta Tokuoka, Takahiro G. Yamada, Daisuke Mashiko, Zenki Ikeda, Noriko F. Hiroi, Tetsuya J. Kobayashi, Kazuo Yamagata & Akira Funahashi. " 3D convolutional neural networks-based segmentation to acquire quantitative criteria of the nucleus during mouse embryogenesis."
NEW PAPER: Yamada TG, Hiki Y, Hiroi NF, Shagimardanova E, Gusev O, Cornette R, et al. (2020) " Identification of a master transcription factor and a regulatory mechanism for desiccation tolerance in the anhydrobiotic cell line Pv11."
NEW BOOK: Translation Supervised by Akira Funahashi "Kazu de Toraeru Saibou Seibutsu gaku (Cell Biology by the Numbers, translated into Japanese)." ISBN 13 : 9784758121064 , Yodosha, published March 13, 2020
NEW PAPER: Tsuyoshi Iwasaki, Ryo Takiguchi, Takumi Hiraiwa, Takahiro G. Yamada, Kazuto Yamazaki, Noriko Hiroi, Akira Funahashi " Neural differentiation dynamics controlled by multiple feedback loop motifs in a comprehensive molecular interaction network."
NEW PAPER: Maya Ooka, Yuta Tokuoka, Shori Nishimoto, Noriko F Hiroi, Takahiro G Yamada, Akira Funahashi. " Deep Learning for Non-Invasive Determination of the Differentiation Status of Human Neuronal Cells by Using Phase-Contrast Photomicrographs."
NEW PAPER: Kaito Ii, Kota Mashimo, Mitsunori Ozeki, Takahiro G Yamada, Noriko F Hiroi and Akira Funahashi. "XitoSBML: a modeling tool for creating spatial SBML models from microscopic images."
NEW PAPER: Akira Funahashi, Yuichiro Nakai, and Noriko Hiroi. "Development of 3D imaging system with electorical focus tunable lens"
NEW PAPER: Nishimoto S, Tokuoka Y, Yamada TG, Hiroi NF, Funahashi A. "Predicting the future direction of cell movement with convolutional neural networks."
NEW PAPER: Hiraiwa T, Yamada TG, Miki N, Funahashi A and Hiroi N. "Activation of cell migration via morphological changes in focal adhesions depends on shear stress in MYCN-amplified neuroblastoma cells."
NEW PAPER: Noriko Hiroi et al. "Temperature change the colour of light - in a small world of a living cell -."
NEW PAPER: Yamada TG, Suetsugu Y, Deviatiiarov R, Gusev O, Cornette R, Nesmelov A, Hiroi N, Kikawada T and Funahashi A. "Transcriptome analysis of the anhydrobiotic cell line Pv11 infers the mechanism of desiccation tolerance and recovery."
NEW PAPER: Hiraiwa T, Nakai Y, Yamada TG, Tanimoto R, Kimura H, Matsumoto Y, Miki N, Hiroi N and Funahashi A. "Quantitative analysis of sensitivity to Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device."
We investigate How is life in the way of Quantitative biology and Systems biology to answer What can make a system lifelike? It is another expression of What is life for us.
We develop/fabricate/use microfluidic device.
We use Qdots, modified GFP, IR laser to control cellular level temperature.
We love optics, taking bioimages, and analyse them.
We use model bacteria, which turn over quickly, to investigate evolution and adaptation.
We build and analyse biological molecular networks.
Working together for specific research projects.