Laboratory of Physical Chemistry for Life Science (Noriko F Hiroi)

Laboratory of Physical Chemistry for Life Science

Sanyo-Onoda City University/Tokyo University of Science, Yamaguchi

News

NEW PAPER: Hiraiwa T, Yamada TG, Miki N, Funahashi A and Hiroi N. "Activation of cell migration via morphological changes in focal adhesions depends on shear stress in MYCN-amplified neuroblastoma cells." Journal of the Royal Society Interface accepted. Feb 12th, 2019; published on line on Mar 6th

NEW PAPER: Noriko Hiroi and Ryu Yamanaka. "Temperature change the colour of light - in a small world of a living cell -." Science Forum volume 409, pages 30-35. Feb 2019 published (in Japanese, a review article); publisher Tokyo University of Science

NEW PAPER: Yamada TG, Suetsugu Y, Deviatiiarov R, Gusev O, Cornette R, Nesmelov A, Hiroi N, Kikawada T and Funahashi A. "Transcriptome analysis of the anhydrobiotic cell line Pv11 infers the mechanism of desiccation tolerance and recovery." Scientific Reports volume 8, 17941 Dec. 19th, 2018 published.

Press Release Dec. 19th, 2018

Nikkei Newsletter Dec. 19th, 2018

NEW PAPER: Yamanaka R, Shindo Y, Hotta K, Suzuki K, Oka K. "GABA-induced intracellular Mg2+ mobilization　integrates and coordinates cellular information　processing for the maturation of neural networks." Current Biology Oct. 18th, 2018 accepted; Dec. 17th, 2018 published.

Press Release Dec. 7th, 2018

see also Signal Transduction: Magnesium Manifests as a Second Messenger. Alessandra Stangherlin, John S. O’Neill

NEW PAPER: Hiraiwa T, Nakai Y, Yamada TG, Tanimoto R, Kimura H, Matsumoto Y, Miki N, Hiroi N and Funahashi A. "Quantitative analysis of sensitivity to Wnt3a gradient in determination of the pole-to-pole axis of mitotic cells by using a microfluidic device." FEBS Open Bio Volume 8, Issue 12, Pages 1920-1935. Sep. 4th, 2018 accepted; Sep. 16th, 2018 first published

What We Do

We investigate How is life in the way of Quantitative biology and Systems biology to answer What can make a system lifelike? It is another expression of What is life for us.

Microfluidics

We develop/fabricate/use microfluidic device.

Intracellular Temperature Detection

We use Qdots, modified GFP, IR laser to control cellular level temperature.

Image Processing

We love optics, taking bioimaging, and analyse them.

Evolution & Adaptation

We use model bacteria, which turn over quickly, to investigate evolution and adaptation.

Network Analyses

We build and analyse biological molecular networks.

Lab Members

Please visit personal page & take a contact directly.

Colaborators

Working together for specific reserahc projects.